A review of the value of quadrivalent influenza vaccines and their potential contribution to influenza control
Identifieur interne : 000347 ( Main/Exploration ); précédent : 000346; suivant : 000348A review of the value of quadrivalent influenza vaccines and their potential contribution to influenza control
Auteurs : Riju Ray [Belgique] ; Gaël Dos Santos ; Philip O. Buck [États-Unis] ; Carine Claeys [Belgique] ; Gonçalo Matias [Belgique] ; Bruce L. Innis [États-Unis] ; Rafik Bekkat-Berkani [Belgique]Source :
- Human Vaccines & Immunotherapeutics [ 2164-5515 ] ; 2017.
Abstract
The contribution of influenza B to the seasonal influenza burden varies from year-to-year. Although 2 antigenically distinct influenza B virus lineages have co-circulated since 2001, trivalent influenza vaccines (TIVs) contain antigens from only one influenza B virus. B-mismatch or co-circulation of both B lineages results in increased morbidity and mortality attributable to the B lineage absent from the vaccine. Quadrivalent vaccines (QIVs) contain both influenza B lineages. We reviewed currently licensed QIVs and their value by focusing on the preventable disease burden. Modeling studies support that QIVs are expected to prevent more influenza cases, hospitalisations and deaths than TIVs, although estimates of the case numbers prevented vary according to local specificities. The value of QIVs is demonstrated by their capacity to broaden the immune response and reduce the likelihood of a B-mismatched season. Some health authorities have preferentially recommended QIVs over TIVs in their influenza prevention programmes.
Url:
DOI: 10.1080/21645515.2017.1313375
PubMed: 28532276
PubMed Central: 5512791
Affiliations:
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Buck</name><affiliation wicri:level="1"><nlm:aff id="af0003"><institution>GSK</institution>, Philadelphia, PA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Claeys, Carine" sort="Claeys, Carine" uniqKey="Claeys C" first="Carine" last="Claeys">Carine Claeys</name><affiliation wicri:level="1"><nlm:aff id="af0001"><institution>GSK</institution>, Wavre,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matias, Goncalo" sort="Matias, Goncalo" uniqKey="Matias G" first="Gonçalo" last="Matias">Gonçalo Matias</name><affiliation wicri:level="1"><nlm:aff id="af0001"><institution>GSK</institution>, Wavre,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Innis, Bruce L" sort="Innis, Bruce L" uniqKey="Innis B" first="Bruce L." last="Innis">Bruce L. Innis</name><affiliation wicri:level="1"><nlm:aff id="af0003"><institution>GSK</institution>, Philadelphia, PA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bekkat Berkani, Rafik" sort="Bekkat Berkani, Rafik" uniqKey="Bekkat Berkani R" first="Rafik" last="Bekkat-Berkani">Rafik Bekkat-Berkani</name><affiliation wicri:level="1"><nlm:aff id="af0001"><institution>GSK</institution>, Wavre,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Human Vaccines & Immunotherapeutics</title><idno type="ISSN">2164-5515</idno><idno type="eISSN">2164-554X</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>ABSTRACT</title><p>The contribution of influenza B to the seasonal influenza burden varies from year-to-year. Although 2 antigenically distinct influenza B virus lineages have co-circulated since 2001, trivalent influenza vaccines (TIVs) contain antigens from only one influenza B virus. B-mismatch or co-circulation of both B lineages results in increased morbidity and mortality attributable to the B lineage absent from the vaccine. Quadrivalent vaccines (QIVs) contain both influenza B lineages. We reviewed currently licensed QIVs and their value by focusing on the preventable disease burden. Modeling studies support that QIVs are expected to prevent more influenza cases, hospitalisations and deaths than TIVs, although estimates of the case numbers prevented vary according to local specificities. The value of QIVs is demonstrated by their capacity to broaden the immune response and reduce the likelihood of a B-mismatched season. 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Lindblade</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, M C" uniqKey="Yang M">M-C Yang</name></author><author><name sortKey="Tan, Ec H" uniqKey="Tan E">EC-H Tan</name></author><author><name sortKey="Su, J J" uniqKey="Su J">J-J Su</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Belgique</li><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Dos Santos, Gael" sort="Dos Santos, Gael" uniqKey="Dos Santos G" first="Gaël" last="Dos Santos">Gaël Dos Santos</name></noCountry><country name="Belgique"><noRegion><name sortKey="Ray, Riju" sort="Ray, Riju" uniqKey="Ray R" first="Riju" last="Ray">Riju Ray</name></noRegion><name sortKey="Bekkat Berkani, Rafik" sort="Bekkat Berkani, Rafik" uniqKey="Bekkat Berkani R" first="Rafik" last="Bekkat-Berkani">Rafik Bekkat-Berkani</name><name sortKey="Claeys, Carine" sort="Claeys, Carine" uniqKey="Claeys C" first="Carine" last="Claeys">Carine Claeys</name><name sortKey="Matias, Goncalo" sort="Matias, Goncalo" uniqKey="Matias G" first="Gonçalo" last="Matias">Gonçalo Matias</name></country><country name="États-Unis"><noRegion><name sortKey="Buck, Philip O" sort="Buck, Philip O" uniqKey="Buck P" first="Philip O." last="Buck">Philip O. Buck</name></noRegion><name sortKey="Innis, Bruce L" sort="Innis, Bruce L" uniqKey="Innis B" first="Bruce L." last="Innis">Bruce L. Innis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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